Overview

Cholestasis of pregnancy is a liver condition that causes severe itching late in pregnancy. It’s also known as intrahepatic cholestasis of pregnancy (ICP) or obstetric cholestasis.

ICP temporarily lowers liver function in some pregnant people. This causes bile to build up in your liver and bloodstream. Bile is a substance produced by your liver and stored in your gallbladder. Every time you eat, bile breaks down fats so you can digest them properly. When levels of bile in your blood reach a certain level, you may begin to itch.

Cholestasis of pregnancy can cause complications for you and the fetus. To lower the risk of complications, your pregnancy care provider may monitor you closely for the remainder of your pregnancy.

What happens if I have cholestasis while pregnant?

During pregnancy, a fetus relies on your liver to remove waste from its blood. If your liver isn’t functioning properly, bile levels may increase to unsafe levels that may stress the fetus’s liver. Your liver is an important organ responsible for removing waste from your body, so when it’s not fully functioning, it can cause complications.

Your pregnancy care provider will monitor you closely to ensure cholestasis doesn’t harm you or the fetus.

How common is cholestasis of pregnancy?

Cholestasis affects about 1 to 2 in 1,000 people during pregnancy. More people are diagnosed with ICP during the winter than other times of the year, but researchers aren’t sure why. Data suggests it’s more common in people of Hispanic and Swedish backgrounds.

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Symptoms

When to see a doctor

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Complications

Blood clots are a dangerous complication of atrial fibrillation (AFib). Blood clots can lead to stroke.
The risk of stroke from AFib increases as you grow older. Other health conditions also may increase the risk of a stroke due to AFib. These conditions include:
  • High blood pressure.
  • Diabetes.
  • Heart failure.
  • Some types of heart valve disease.
Blood thinners are commonly prescribed to prevent blood clots and strokes in people with atrial fibrillation.

Prevention

Healthy lifestyle choices can reduce the risk of heart disease and may prevent atrial fibrillation (AFib). Here are some basic heart-healthy tips:
  • Control high blood pressure, high cholesterol and diabetes.
  • Don't smoke or use tobacco.
  • Eat a diet that's low in salt and saturated fat.
  • Exercise at least 30 minutes a day on most days of the week unless your health care team says not to.
  • Get good sleep. Adults should aim for 7 to 9 hours daily.
  • Maintain a healthy weight.
  • Reduce and manage stress.


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