Overview
Diphtheria is a serious bacterial infection caused by Corynebacterium diphtheriae that primarily affects the throat and upper airways. The bacteria produce a toxin that can lead to severe illness and life-threatening complications. Diphtheria is highly contagious but largely preventable through vaccination.
Symptoms
Symptoms usually develop gradually and can worsen if untreated:
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Sore throat
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Fever and chills
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Thick gray or white coating on the throat or tonsils
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Difficulty swallowing
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Hoarseness
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Swollen lymph nodes in the neck
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Breathing difficulty in severe cases
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Fatigue and weakness
Causes
Diphtheria is caused by bacterial infection and toxin production:
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Infection with Corynebacterium diphtheriae
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Spread through respiratory droplets from coughing or sneezing
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Contact with contaminated objects
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Lack of immunity due to incomplete vaccination
Risk Factors
Certain factors increase the risk of diphtheria:
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Incomplete or lack of vaccination
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Living in crowded or unsanitary conditions
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Poor access to healthcare
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Travel to areas where diphtheria is more common
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Weakened immune system
Complications
Diphtheria can lead to severe and potentially fatal complications:
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Airway obstruction
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Heart inflammation and rhythm disturbances
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Nerve damage causing paralysis
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Kidney damage
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Respiratory failure
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Increased risk of death if untreated
Prevention
Prevention focuses on immunization and infection control:
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Receiving recommended diphtheria vaccinations
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Keeping vaccinations up to date with booster doses
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Practicing good hygiene
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Avoiding close contact with infected individuals
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Prompt treatment and isolation of suspected cases
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