Overview

Diphtheria is a serious bacterial infection caused by Corynebacterium diphtheriae that primarily affects the throat and upper airways. The bacteria produce a toxin that can lead to severe illness and life-threatening complications. Diphtheria is highly contagious but largely preventable through vaccination.

Symptoms

Symptoms usually develop gradually and can worsen if untreated:

  • Sore throat

  • Fever and chills

  • Thick gray or white coating on the throat or tonsils

  • Difficulty swallowing

  • Hoarseness

  • Swollen lymph nodes in the neck

  • Breathing difficulty in severe cases

  • Fatigue and weakness

Causes

Diphtheria is caused by bacterial infection and toxin production:

  • Infection with Corynebacterium diphtheriae

  • Spread through respiratory droplets from coughing or sneezing

  • Contact with contaminated objects

  • Lack of immunity due to incomplete vaccination

Risk Factors

Certain factors increase the risk of diphtheria:

  • Incomplete or lack of vaccination

  • Living in crowded or unsanitary conditions

  • Poor access to healthcare

  • Travel to areas where diphtheria is more common

  • Weakened immune system

Complications

Diphtheria can lead to severe and potentially fatal complications:

  • Airway obstruction

  • Heart inflammation and rhythm disturbances

  • Nerve damage causing paralysis

  • Kidney damage

  • Respiratory failure

  • Increased risk of death if untreated

Prevention

Prevention focuses on immunization and infection control:

  • Receiving recommended diphtheria vaccinations

  • Keeping vaccinations up to date with booster doses

  • Practicing good hygiene

  • Avoiding close contact with infected individuals

  • Prompt treatment and isolation of suspected cases


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