Overview

Dupuytren contracture (sometimes also called Dupuytren disease) is a genetic disorder that makes the tissue under the skin of your palms and fingers thicken and tighten. Small bumps (nodules) grow on your hand’s fascia — the rubber-band like tissue under your skin that supports your hand and fingers. Eventually, these growths can form thick cords under your skin and bend your fingers so much that you can’t straighten them.

The growths that cause Dupuytren contracture are always benign, which means they’re never a symptom (or cause) of cancer. You might need surgery, but many cases can be managed with more conservative treatments.

Who does Dupuytren contracture affect?

Dupuytren contracture can affect anyone. Some people are more likely to develop it, including:

  • People assigned male at birth (AMAB).
  • People of European descent.
  • People with a family member who’s had it.

Dupuytren contracture and other conditions

People with certain diseases or health conditions may be more likely to develop Dupuytren contracture, including:

  • Diabetes.
  • Epilepsy and other seizure disorders.
  • Alcohol use disorder (formerly known as alcoholism).
  • HIV and AIDS.
  • Vascular disease.

How common is Dupuytren contracture?

Dupuytren contracture is rare. Around 5% of people experience it. People of European descent are much more likely to develop Dupuytren contracture than people from other ethnic backgrounds.

How does Dupuytren contracture affect my body?

Dupuytren contracture might never affect your body in a way you notice. If you have mild symptoms, you may never even know you have it. Even if you do have symptoms, it usually takes a long time (months or years) for them to progress (get worse). In later stages, it might be hard — or impossible — to straighten your affected fingers.

Dupuytren contracture can affect any of your fingers — including your thumb. It’s most common in people’s fingers in the following order:

  • Ring (fourth finger).
  • Pinkie (fifth finger).
  • Middle (third finger).
  • Index (second finger).
  • Thumb (first finger).

Can Dupuytren contracture affect other parts of the body?

Dupuytren contracture can only affect your hands. It can’t develop in other parts of your body. Even though it’s related to other connective tissue disorders that can develop in other places in your body, you’ll never develop Dupuytren contracture anywhere other than your hands.

Some people with Dupuytren contracture are more likely to experience similar conditions like Ledderhose disease and Peyronie’s disease.

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Symptoms

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Complications

Blood clots are a dangerous complication of atrial fibrillation (AFib). Blood clots can lead to stroke.
The risk of stroke from AFib increases as you grow older. Other health conditions also may increase the risk of a stroke due to AFib. These conditions include:
  • High blood pressure.
  • Diabetes.
  • Heart failure.
  • Some types of heart valve disease.
Blood thinners are commonly prescribed to prevent blood clots and strokes in people with atrial fibrillation.

Prevention

Healthy lifestyle choices can reduce the risk of heart disease and may prevent atrial fibrillation (AFib). Here are some basic heart-healthy tips:
  • Control high blood pressure, high cholesterol and diabetes.
  • Don't smoke or use tobacco.
  • Eat a diet that's low in salt and saturated fat.
  • Exercise at least 30 minutes a day on most days of the week unless your health care team says not to.
  • Get good sleep. Adults should aim for 7 to 9 hours daily.
  • Maintain a healthy weight.
  • Reduce and manage stress.


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