Gallstones

Gallstones are hardened, concentrated pieces of bile that form in your gallbladder or bile ducts. “Gall” means bile, so gallstones are bile stones. Your gallbladder is your bile bladder. It holds and stores bile for later use. Your liver makes bile, and your bile ducts carry it to the different organs in your biliary tract.

Healthcare providers sometimes use the term “cholelithiasis” to describe the condition of having gallstones. “Chole” also means bile, and “lithiasis” means stones forming. Gallstones form when bile sediment collects and crystallizes. Often, the sediment is an excess of one of the main ingredients in bile.

How serious are gallstones?

Gallstones (cholelithiasis) won’t necessarily cause any problems for you. A lot of people have them and never know it. But gallstones can become dangerous if they start to travel through your biliary tract and get stuck somewhere. They can clog up your biliary tract, causing pain and serious complications.

The problem with gallstones is that they grow — slowly, but surely — as bile continues to wash over them and leave another layer of sediment. What begins as a grain of sand can grow big enough to stop the flow of bile, especially if it gets into a narrow space, like a bile duct or the neck of your gallbladder.

How common are gallstones (cholelithiasis)?

At least 10% of U.S. adults have gallstones, and up to 75% of them are women and people assigned female at birth (AFAB). But only 20% of those diagnosed will ever have symptoms or need treatment for gallstones.