Overview

Diagnosis

Diagnosis of BPH typically starts with a medical history review and a physical exam, including:

  • Digital Rectal Exam (DRE): To check prostate size and texture.

  • Urine Test: Screens for infections or other conditions with similar symptoms.

  • Blood Test: Evaluates kidney function and may include prostate-specific antigen (PSA) to assess prostate health.

Additional tests may include:

  • Urinary Flow Test: Measures strength and volume of urine flow.

  • Postvoid Residual Volume Test: Determines how completely the bladder empties.

  • 24-hour Voiding Diary: Tracks urination patterns, especially nighttime urine output.

  • Transrectal Ultrasound (TRUS): Uses sound waves to measure prostate size.

  • Prostate Biopsy: Samples tissue to rule out cancer.

  • Urodynamic and Pressure Flow Studies: Measures bladder muscle function.

  • Cystoscopy: Uses a lighted scope to examine the urethra and bladder.


Treatment

Treatment depends on prostate size, symptoms, overall health, and personal preference. Mild symptoms may not require immediate treatment.

1. Medications

  • Alpha Blockers: Relax bladder and prostate muscles to improve urine flow (e.g., tamsulosin, alfuzosin). Side effects may include dizziness and retrograde ejaculation.

  • 5-Alpha Reductase Inhibitors: Shrink the prostate over several months (e.g., finasteride, dutasteride). Possible sexual side effects.

  • Combination Therapy: Using both alpha blockers and 5-alpha reductase inhibitors if single therapy is insufficient.

  • Tadalafil (Cialis): Can improve urinary symptoms and erectile dysfunction.

2. Minimally Invasive Procedures & Surgery
Procedures may be needed if medications fail or complications arise. Options include:

  • Transurethral Resection of the Prostate (TURP): Removes inner prostate tissue.

  • Transurethral Incision of the Prostate (TUIP): Small cuts in the prostate to improve urine flow.

  • Transurethral Microwave Therapy (TUMT): Uses microwave energy to shrink prostate tissue.

  • Laser Therapy: High-energy lasers destroy or remove excess tissue (PVP, HoLEP).

  • Prostate Lift: Compresses the prostate to ease urine flow with fewer sexual side effects.

  • Water Vapor Thermal Therapy (WVTT): Uses steam to remove excess tissue.

  • Robotic Waterjet Treatment: Water jets remove obstructive tissue.

  • Open or Robot-Assisted Prostatectomy: Surgical removal for very large prostates.

  • Prostate Artery Embolization (PAE): Blocks blood flow to shrink the prostate; performed by a trained interventional radiologist.

Potential Side Effects:

  • Retrograde ejaculation

  • Urinary leakage

  • Urinary tract infection

  • Bleeding

  • Erectile dysfunction


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