Overview

Diagnosis

To diagnose an enlarged heart (cardiomegaly), your health care provider will typically perform a physical examination and discuss your medical history and symptoms.

Tests commonly used to determine the presence and cause of an enlarged heart include:

  • Blood tests: Help detect conditions that can cause heart enlargement or confirm a heart attack by identifying substances from damaged heart muscle.

  • Chest X-ray: Shows the size and shape of the heart. If the heart appears enlarged, additional tests are performed to confirm.

  • Electrocardiogram (ECG or EKG): Measures the heart’s electrical activity to detect abnormal rhythms or signs of thickened heart muscle.

  • Echocardiogram: Uses sound waves to create images of the heart’s structure, motion, and blood flow to assess heart function.

  • Exercise or stress tests: Evaluate how the heart responds to physical activity. If unable to exercise, medicines are used to mimic the effects of exercise.

  • Cardiac CT scan or MRI: Creates detailed images of the heart to assess size, structure, and abnormalities.

  • Cardiac catheterization: Involves inserting a thin tube through a blood vessel into the heart to measure pressure, assess blood flow, and possibly collect a tissue sample (biopsy).


Treatment

Treatment for an enlarged heart focuses on addressing the underlying cause and improving heart function.

Medications

  • Diuretics: Help remove excess fluid and sodium, reducing heart workload.

  • Beta blockers, ACE inhibitors, or ARBs: Lower blood pressure and improve heart function.

  • Blood thinners (anticoagulants): Prevent blood clots that may lead to heart attack or stroke.

  • Anti-arrhythmics: Help regulate abnormal heart rhythms.


Surgery and Procedures

If medications alone are insufficient, surgical or device-based treatments may be necessary:

  • Pacemaker: Regulates heart rate and ensures consistent heartbeat.

  • Implantable cardioverter-defibrillator (ICD): Monitors heart rhythm and delivers electric shocks if life-threatening arrhythmias occur.

  • Heart valve surgery: Repairs or replaces damaged valves that contribute to heart enlargement.

  • Coronary bypass surgery: Restores blood flow by rerouting around blocked coronary arteries.

  • Left ventricular assist device (LVAD): A mechanical pump that helps the heart circulate blood, often used before or instead of a transplant.

  • Heart transplant: Considered the final option when all other treatments fail, though donor heart availability can be limited.


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