Overview

Diagnosis of Antibiotic-Associated Diarrhea

Your healthcare professional will begin by asking about your symptoms and reviewing your recent diet, antibiotic use, and overall health history.

Stool testing
A sample of your stool may be sent to a laboratory to check for infections, including Clostridioides difficile (C. difficile), which can cause more severe antibiotic-associated diarrhea.


Treatment of Antibiotic-Associated Diarrhea

Treatment depends on the severity of symptoms and whether a C. difficile infection is present.

Mild diarrhea management

  • Most mild cases resolve within a few days during or after antibiotic use.

  • Your doctor may recommend switching to a different antibiotic if diarrhea persists.

  • Maintaining hydration is important to prevent complications from fluid loss.

Treatment for C. difficile infection

  • The original antibiotic may need to be stopped.

  • Your healthcare professional may prescribe specific antibiotics that target C. difficile bacteria.

  • Medications that lower stomach acid may be paused to support recovery.

Managing recurrent or severe infections

  • Recurring C. difficile infections may require additional treatments, such as fecal microbiota transplantation to restore healthy gut bacteria.

  • In severe cases, surgery may be necessary to remove damaged sections of the colon.


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