Antiphospholipid Syndrome

Diagnosis of Antiphospholipid Syndrome

If you experience unexplained blood clots or recurrent pregnancy loss, consult your healthcare professional. Diagnosis involves:

Blood tests for antibodies

• Tests are done to check for antiphospholipid antibodies and clotting problems.

• For a confirmed diagnosis, antibodies must be present in your blood at least twice, with tests conducted 12 or more weeks apart.

Important considerations

• Some people may have antiphospholipid antibodies without symptoms.

• A diagnosis is made only when these antibodies cause health complications, such as clotting disorders or pregnancy-related issues.

Treatment of Antiphospholipid Syndrome

Treatment focuses on preventing and managing blood clots and reducing pregnancy complications.

Blood-thinning medications

• Heparin: Fast-acting, delivered via injections.

• Warfarin (Jantoven): Oral medication that takes several days to take effect.

• Aspirin: Used to prevent blood clots in certain cases.

• Regular blood tests monitor dosage to maintain safe clotting levels and reduce bleeding risks.

Additional treatments

• Some studies suggest that hydroxychloroquine (Plaquenil), rituximab (Rituxan), eculizumab (Soliris), and statins may be beneficial, though further research is needed.

Treatment During Pregnancy

• Heparin, sometimes combined with aspirin, is typically used to support a successful pregnancy.

• Warfarin is avoided during pregnancy due to its potential harm to the fetus.

• With careful management, successful pregnancies are possible for individuals with antiphospholipid syndrome.